Structure of PDB 7z5h Chain A Binding Site BS01

Receptor Information
>7z5h Chain A (length=332) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIH
QAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCAGEV
VVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRG
VNNARQPWHNAEGRLRYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLY
YTIHRAARMSFRQLFQDLERYVQDADVRWEYCVRAKRGQTDTSLPGCFSK
DQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPH
FMQDLARYRQQLEHIMATNRLDEAELGRLLPD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7z5h Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7z5h Posttranslational modification of microtubules by the MATCAP detyrosinase.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H280 H285 E316
Binding residue
(residue number reindexed from 1)		H141 H146 E177
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.17.17: tubulinyl-Tyr carboxypeptidase.
External links
PDB RCSB:7z5h, PDBe:7z5h, PDBj:7z5h
PDBsum7z5h
PubMed35482892
UniProtQ68EN5|MACA1_HUMAN Microtubule-associated tyrosine carboxypeptidase 1 (Gene Name=MATCAP1)

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