Structure of PDB 7z11 Chain A Binding Site BS01

Receptor Information
>7z11 Chain A (length=727) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLPAEFITRPHPSKDHGKETCTAYIHPNVLSSLEINPGSFCTVGKIGENG
ILVIARAGDEEVHPVNVITLSTTIRSVGNLILGDRLELKKAQVQPPYATK
VTVGSLQGYNILECMEEKVIQKLLDDSGVIMPGMIFQNLKTKAGDESIDV
VITDASNLFYLSPPFIFRKGSTHITFSKETQANRKYNLPEPLSYAAVGGL
DKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVA
NTSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEIDSI
APNRANDDSGEVESRVVATLLTLMDGMGAAGKVVVIAATNRPNSVDPALR
RPGRFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIKYIASKTH
GYVGADLTALCRESVMKTIQRGLGTDANIDKFSLKVTLKDVESAMVDIRP
SAMREIFLEMPKVYWSDIGGQEELKTKMKEMIQLPLEASETFARLGISAP
KGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESERAIRE
IFRKARSAAPSIIFFDEIDALSPDRDGSSTSAANHVLTSLLNEIDGVEEL
KGVVIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLEILKKCTKKF
NTEESGVDLHELADRTEGYSGAEVVLLCQEAGLAAIMEDLDVAKVELRHF
EKAFKGIARGITPEMLSYYEEFALRSG
Ligand information
>7z11 Chain G (length=20) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB7z11 Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K318 K589 Y590 V591 S629
Binding residue
(residue number reindexed from 1)		K268 K539 Y540 V541 S579
Enzymatic activity
Enzyme Commision number 3.6.4.10: non-chaperonin molecular chaperone ATPase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009410 response to xenobiotic stimulus
GO:0034214 protein hexamerization
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7z11, PDBe:7z11, PDBj:7z11
PDBsum7z11
PubMed36097293
UniProtP32794|AFG2_YEAST ATPase family gene 2 protein (Gene Name=AFG2)

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