Structure of PDB 7yzp Chain A Binding Site BS01

Receptor Information
>7yzp Chain A (length=381) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVF
DTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNQDSVATLNESRDIMAFL
NTTVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQ
QHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVTLDAFPAQNFPP
ADYIALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGK
LESVENLNVPVTQPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTD
EYLHDIQRKIQALTESLPVEVLLVRRSREQRERVLASQQRETLSELSVEE
VFNRRLALEELDESQQQRLQHLFTTTLHTLA
Ligand information
>7yzp Chain F (length=59) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagaagccagacattaacgcttctggatagcgtccagaagcgttaatgtc
tggcttctg
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7yzp Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		Y16 R225 R342
Binding residue
(residue number reindexed from 1)		Y16 R211 R328
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0016787 hydrolase activity
GO:1990238 double-stranded DNA endonuclease activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006260 DNA replication
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:1990391 DNA repair complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7yzp, PDBe:7yzp, PDBj:7yzp
PDBsum7yzp
PubMed35987200
UniProtP0AG76|SBCD_ECOLI Nuclease SbcCD subunit D (Gene Name=sbcD)

[Back to BioLiP]