Structure of PDB 7yxw Chain A Binding Site BS01
Receptor Information
>7yxw Chain A (length=128) Species:
9606
(Homo sapiens) [
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IILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKGKRGWI
PASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEV
IHKLLDGWWVIRKDDVTGYFPSMYLQKS
Ligand information
>7yxw Chain D (length=11) Species:
9606
(Homo sapiens) [
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PPSNPPPRPPA
Receptor-Ligand Complex Structure
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PDB
7yxw
Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
W193 W204 S208 E241 D243 E244 D261 W263 Y274 M278 Y279
Binding residue
(residue number reindexed from 1)
W38 W49 S53 E86 D88 E89 D106 W108 Y119 M123 Y124
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7yxw
,
PDBe:7yxw
,
PDBj:7yxw
PDBsum
7yxw
PubMed
UniProt
P14598
|NCF1_HUMAN Neutrophil cytosol factor 1 (Gene Name=NCF1)
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