Structure of PDB 7yvb Chain A Binding Site BS01

Receptor Information
>7yvb Chain A (length=471) Species: 6500 (Aplysia californica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKVIWALMVIIGFTAATLQLSLLVRKYLQFQVVELSEIKDSMPVEYPSVT
ICNIEPISLRKIRKAYNKNESQNLKDWLNFTQTFHFKDMSFMNSIRAFYE
NLGSDAKKISHDLRDLLIHCRFNREECTTENFTSSFDGNYFNCFTFNGGQ
LRDQLQMHATGPENGLSLIISIEKDEPLPGTYGVYNFENNILHSAGVRVV
VHAPGSMPSPVDHGFDIPPGYSSSVGLKALLHTRLSEPYGNCTEDSLEGI
QTYRNTFFACLQLCKQRRLIRECKCKSSALPDLSVENITFCGVIPDWKDI
RRNVTGEYKMNQTIPTISLACEARVQKQLNNDRSYETECGCYQPCSETSY
LKSVSLSYWPLEFYQLSALERFFSQKNPTDQQHFMKIAQDFLSRLAHPQT
SYSLSEKEMAKEASDLIRQNLLRLNIYLEDLSVVEYRQLPAYGLADLFAD
IGGTLGLWMGISVLTIMELME
Ligand information
Receptor-Ligand Complex Structure
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PDB7yvb Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Y156 L164 L168 N183 S184 I185 F188 G270 T271 Y272 V274
Binding residue
(residue number reindexed from 1)		Y66 L74 L78 N93 S94 I95 F98 G180 T181 Y182 V184
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005272 sodium channel activity
GO:0015280 ligand-gated sodium channel activity
Biological Process
GO:0006814 sodium ion transport
GO:0034220 monoatomic ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7yvb, PDBe:7yvb, PDBj:7yvb
PDBsum7yvb
PubMed37550431
UniProtQ4TZI8

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