Structure of PDB 7yoh Chain A Binding Site BS01

Receptor Information
>7yoh Chain A (length=308) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVW
QAEKDGTLTKGKEIVDATSGNTGIALAYVAAARGYKLTLTMPETMSLERK
RLLCGLGVNLVLTEGAKGMKGAIAKAEEIVASDPSRYVMLKQFENPANPQ
IHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVA
VEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDS
DTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSA
SERYLSTA
Ligand information
>7yoh Chain P (length=7) Species: 71421 (Haemophilus influenzae Rd KW20) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DGMNLNI
Receptor-Ligand Complex Structure
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PDB7yoh Crystal structure of I88L single mutant of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high-affinity inhibitory peptide from serine acetyltransferase of Salmonella typhimurium at 2.14 A
Resolution2.5 Å
Binding residue
(original residue number in PDB)		X42 T69 S70 G71 T73 K118 M120 H224 G228
Binding residue
(residue number reindexed from 1)		X41 T68 S69 G70 T72 K117 M119 H223 G227
Enzymatic activity
Enzyme Commision number 2.5.1.47: cysteine synthase.
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7yoh, PDBe:7yoh, PDBj:7yoh
PDBsum7yoh
PubMed
UniProtP45040|CYSK_HAEIN Cysteine synthase (Gene Name=cysK)

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