Structure of PDB 7yh5 Chain A Binding Site BS01

Receptor Information
>7yh5 Chain A (length=169) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAADAPVLLS
SDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKLRTAGPWESEQ
THDSLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVLFHARIAEDAS
QSPFTIDDVADTLMRKLGN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7yh5 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7yh5 Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		E119 E122 E138 D141
Binding residue
(residue number reindexed from 1)		E112 E115 E131 D134
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.8: ATP diphosphatase.
External links
PDB RCSB:7yh5, PDBe:7yh5, PDBj:7yh5
PDBsum7yh5
PubMed36937295
UniProtP96379|MAZG_MYCTU Nucleoside triphosphate pyrophosphohydrolase (Gene Name=mazG)

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