Structure of PDB 7yg6 Chain A Binding Site BS01

Receptor Information
>7yg6 Chain A (length=727) Species: 31330 (Ephydatia fluviatilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRGSSGQPVPVSANYLPLKGNMDGVFKYAVGFNPPVEDIRSRSQLLNEHK
ELIGLTRVFDGSTLYVPKRICEQRLDLMSTRQTDGASIKVTISLVDSVKN
RDVVQLMNVIFKRILRSLKLQRIGRDYYDANSPLEVPQHKMQLWPGYVTA
INRHEGGLMLVLDVSHRVMKTDTALDFLYELYAFKQLVGSVVLTRYNNRT
YEIDDIAWDKNPRCAFQDHAGSQITFVDYYKRAYDLDITDLEQPLLIHRP
MVCLVPELCAMTGLTDAARSDFKVMKDLAVHTRVPPEKRAESFRKFIQRL
NTTKEASELLHSWGLVLDSRMLDMQGRRLPPEKILFKHSSIVANMEADWS
RECLKEHVISAVSLLDWAVLFVRKDQGKATDFVNMLSKVCPPIGMEVHEP
KMVEVVNDRTESYLRALRELIAPRLQMVVIVFPTSRDDRYSAVKKLCCIE
SPIPSQVLIARTITQQQKLRSVAQKVALQMNAKLGGELWAVEIPLKSCMV
VGIDVYHDKSYGNKSIAGFVASTNPSFTRWYSRTAMQELIHELKLCMQAA
LKKYNEMNQSLPERIIVFRDGVGEGREEYVSEFEVPQFNSCFSIFGENYC
PKLAVVVVQKRITTRIFGRSGHSYDNPPPGVIVDHTITKSYDFYLVSQHV
RQGTVSPTYYRVIYDKSGLKPDHLQRLTYKLTHMYYNWPGTIRTPAPCKY
AHKLAFLVGKSLHRDPAHELSDRLFFL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7yg6 Structure basis of mammalian Piwi-piRNA silencing machinery
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Y435 R438 Y440 F455 F465 Y468 C509 R539 S691 D693 Y696 K700 Q712 V713 I715 T718 K731 Q735 Q908 R911 Y945 N947 W948
Binding residue
(residue number reindexed from 1)		Y196 R199 Y201 F216 F226 Y229 C253 R283 S435 D437 Y440 K444 Q456 V457 I459 T462 K475 Q479 Q648 R651 Y685 N687 W688
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7yg6, PDBe:7yg6, PDBj:7yg6
PDBsum7yg6
PubMed38658622
UniProtD5MRY8

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