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Receptor Information

>7y7t Chain A (length=937) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

APVAARLRNIWPKFPKWLHEAPLAVAWEVTRLFMHCKVDLEDESLKYDPS
WSTARDVTDIWKTLDAFRPEKPPNDVFVTAMTGNFESKGSAVVLSAVLDY
NPDNSPAPLYLVKLKPLMFEQGCRLTRRFGPDRFFEILIPSPTSPSVPPV
VSKQAVEEVIQWLTMGQHSLVGRQWRAFFAKDAIIKERVHFFAETGITFR
PEPVEQRTEFKVSQMLDWLLQLDNNTWQPHLKLFSRIQLGLSKTYAIMTL
EPHQIRHHKTDLLSPSGTGEVMNDGVGRMSRSVAKRIRDVLGLGDVPSAV
QGRFGSAKGMWVIDVDDTGDEDWIETYPSQRKWECDFVDKHQRTLEVRSV
ASELKSAGLNLQLLPVLEDRARDKVKMRQAIGDRLINDLQRQFSEQKHAL
NRPVEFRQWVYESYSSRATRVSHGRVPFLAGLPDSQEETLNFLMNSGFDP
KKQKYLQDIAWDLQKRKCDTLKSKLNIRVGRSAYIYMIADFWGVLEENEV
HVGFSSKFRDEEESFTLLSDCDVLVARSPAHFPSDIQRVRAVFKPELHSL
KDVIIFSTKGDVPLAKKLSGGDYDGDMAWVCWDPEIVDGFVNAEMPLEPD
LSRYLKKDKTTFKQLMASHGTGSAAKEQTTYDMIQKSFHFALQPNFLGMC
TNYKERLCYINNSVSNKPAIILSSLVGNLVDQSKQGIVFNEASWAQLRRE
LLGGALSLPDPMYKSDSWLGRGEPTHIIDYLKFSIARPAIDKELEAFHNA
MAHFWDPDLASYYTFFKEISDKSRSSALLFTTLKNRIGEVEKEYGNKSKD
PYPVRVNQVYEKWCAITPEANYDSKVIRLLELSFLADREMNTWALLRAST
AFKLYYHKSPKFVWQMAGRQLAYIKAQMTSRPGEGAPALMTAFMYAGLMP
DKKFTKQYVARLEGDGSEYPDPEVYEDGIGFTGNGDY

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7y7t Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	R783 K909 Y919 L1082 G1083 M1084 N1087 R1091 D1145
Binding residue (residue number reindexed from 1)	R348 K474 Y484 L647 G648 M649 N652 R656 D710

Enzyme Commision number

2.7.7.48: RNA-directed RNA polymerase.

	Molecular Function
GO:0003968	RNA-dependent RNA polymerase activity

PDB	RCSB:7y7t, PDBe:7y7t, PDBj:7y7t
PDBsum	7y7t
PubMed	36039765
UniProt	Q9Y7G6

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Structure of PDB 7y7t Chain A Binding Site BS01