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Receptor Information

>7y7q Chain A (length=951) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

APVVAARLRNIWPKFPKWLHEAPLAVAWEVTRLFMHCKVDLEDESGLKYD
PSWSTARDVTDIWKTLYLDAFRPEKPPNDVFVTAMTGNFESKGSAVVLSA
VLDYNPDNSPTAPLYLVKLKPLMFEQGCRLTRRFGPDRFFEILIPSPTST
SPSVPPVVSKQGAVEEVIQWLTMGQHSLVGRQWRAFFAKDAGYRKPLREF
QPKPIIKERVHFFAETGITFRPEPVEQRTEFKVSQMLDWLLQLDNNTWQP
HLKLFSRIQLGLSKTYAIMTLEPHQIRHHKTDLLSPSGTGEVMNDGVGRM
SRSVAKRIRDVLGLGDVPSAVQGRFGSAKGMWVIDVDDTGDEDWIETYPS
QRKWECDFVDKHQRTLEVRSVASELKSAGLNLQLLPVLEDRARDKVKMRQ
AIGDRLINDLQRQFSEQKHALNRPVEFRQWVYESYSSRATRVSHGRVPFL
AGLPDSQEETLNFLMNSGFDPKKQKYLQDIAWDLQKRKCDTLKSKLNIRV
GRSAYIYMIADFWGVLEENEVHVGFSSKFRDEEESFTLLSDCDVLVARSP
AHFPSDIQRVRAVFKPELHSLKDVIIFSTKGDVPLAKKLSGGDYDGDMAW
VCWDPEIVDGFVNAEMPLEPDLSRYLKKDKTTFKQLMASHGTGSAAKEQT
TYDMIQKSFHFALQPNFLGMCTNYKERLCYINNSVSNKPAIILSSLVGNL
VDQSKQGIVFNEASWAQLRRELLGGALSLPDPMYKSDSWLGRGEPTHIID
YLKFSIARPAIDKELEAFHNAAHFWDPDLASYYTFFKEISDKSRSSALLF
TTLKNRIGEVEKEYGRLVKNSKDPYPVRVNQVYEKWCAITPESKVIRLLE
LSFLADREMNTWALLRASTAFKLYYHKSPKFVWQMAGRQLAYIKAQMTSR
PGEGAPALMTAFMYAGLMPDKKFTKQYVARLEEYPDPEVYDGIGFTGNGD
Y

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7y7q Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Resolution	2.05 Å
Binding residue (original residue number in PDB)	Y590 K790 Q797 A853 T854 Y919 S963 L1082 G1083 M1084 T1086 N1087 R1091
Binding residue (residue number reindexed from 1)	Y193 K376 Q383 A439 T440 Y505 S549 L668 G669 M670 T672 N673 R677

Enzyme Commision number

2.7.7.48: RNA-directed RNA polymerase.

	Molecular Function
GO:0003968	RNA-dependent RNA polymerase activity

PDB	RCSB:7y7q, PDBe:7y7q, PDBj:7y7q
PDBsum	7y7q
PubMed	36039765
UniProt	Q9Y7G6

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Structure of PDB 7y7q Chain A Binding Site BS01