Structure of PDB 7y5p Chain A Binding Site BS01

Receptor Information
>7y5p Chain A (length=338) Species: 66854 (Saccharothrix mutabilis subsp. capreolus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTAIREIRLSEPESAQAALLALECAQRYAEPDSADFLADAAVLAHDLPRA
VRREVERARLDDRLHALVVRGNDVDQDALGPTPPHWRQARTAASRRYGFL
LVLYASLLGDVVGWATQQDGRVVTDVLPIEGQEDSLVSSSSSVELGWHTE
DAFSPYRADYVGLFSLRNPDSVATTVAGLDPDLVGPAVVDVLFGERFHIR
PDNSHLPTHNSGGRLSDYFAGIVEAVENPRAVSILRGHRDAPQLCVDSDF
TTAVDGDAEAAGALDTLIKHLGGALYEVVLGPGDVAFLDNRNVVHGRRPF
RARFDGTDRWLKRINVTADLRKSRAARRDAQARVLGEA
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7y5p Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7y5p Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H148 E150 H295
Binding residue
(residue number reindexed from 1)		H148 E150 H295
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7y5p, PDBe:7y5p, PDBj:7y5p
PDBsum7y5p
PubMed36176888
UniProtA6YEH4

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