Structure of PDB 7xzi Chain A Binding Site BS01

Receptor Information
>7xzi Chain A (length=1598) Species: 3055 (Chlamydomonas reinhardtii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLVTSVKDYVEITHKLIEIEPLKNYTEFGAVFTYFIFSIGEFFKNFFSFS
FLNNIWSIPIIIPDIASAMISEVSVLDGYFHNAFTFLETSVNTTTNPSLV
IFEKFVIGIINSLFLILPTSTSHLITLRRFVMQGLEAGYMAGLGTLAGNF
LWLASIILGWRFFVIPWLSLDIFRYLLGFVLLVKYIWDSSKERRMALEDL
SKWKIFLLNFLLALTEQSCIYPFISNLSFGPDASILEGFPVDNYPQFLLI
HGAYLLGILFGSFSLLQFTCWFWENPAFSIYLWITTKSSLKISTSSYYKI
LNFTFLYATMLCAIASIPYYGLDYTITNPIGLVPQDRILNQKKSQSDPDK
LITETAFLNLNPTDKNSRIRDGVHARRERWKQRLIKYQAFDASTYDQGVY
DFLTIEDLNYGFDRFWLRRKMRNHQIRFRLFPGPWMRSLKKQLASGPRVE
FFRILFEQFYHPNFHDRAIEGLVLTNTQATLLPTDLQTKRTIKPGLIYTN
SALRKFVRNVNTRLNLKLLNSKETNLTTKYKSQFIYSKRWKSIFSKIQPL
QNGTTRKSYQLFRNVAKQILVTPDAKSLKLITINQKLSLKERKLLELRTQ
YNNNTLVRPLNVYLQKEEAFKRKLRYYGTMPMRKLTVGNQAPYFKALMKR
GFYYYKPTLRWRKTLYVASLRRGFRKKSRKQRILVMPDGENSLITKPTHS
YTVLGKRASRYRHQIYKDVLQHWYYTPFNRLLMKFDVDAFINRQPKSHFL
TKNEERALHIRRFLLSEHYDTLRWYTYMQHYKTMKTNIGGTKSFANRAYN
QQFQGTFKKIRHLFAITPKQGDFYTLKFDQPLYNDNKLKDNLYFHEELLT
KLNFVYSELFVKLIKECKKRIHDQTFLKNYITHRIEKREQLNQEQTKELN
KRLEKLKVWLNSDKGSSPDKVLTTAMQKAVNESISLSGIMPSDKIKTTYG
NLTNAYTIKTENAILTKLNVINQLTNNELRVKTDKDLQWWRTKQRVITKR
KSARKRDRFKKQIAVVNKKLAALSKKVETEKSNLYQTLYGNYFFAKKLRK
KISSKGRRYRSLSLARYLTATRKPRLVGLDNLTKIDNITTLQGAFITKEE
KQDSLNLTIQRKQELTNSLKKSQIKKRSRHSWKKRSRHQFSRNHYKYRKR
HTHGNGKLRVMNKKLKKFKATNELRQWWWNSFLPRYLSNLQVNKNVSFKP
LSNTMNQNIVTESVKVETNQVYLPEGEKSFDITSMTTTLPFYAGWDESLK
KFVVTNRLLSRRDAGLSVNNNPQEINFTNPPIQGLNEGSFLYWQTEMPFN
SYNIDQFITTNQSFYAPLGWRRFEFRHSILKTWVNKKTLIISLKNLQPLK
SSQQKQNQIKTKKLVARRIKKRYKLLKQMPNQLMYSPTGPLLTEVLPSHY
ISVFDQQYRLPRNRYLKRNPLKTLKKTTLLALMDSSKQTNGVNKEFTLRK
RVKPRRKYHRKRFIKKDGLIFPRRTKFNTEEDDLRWRPSSRTKLRQLRRR
EFQQVLKPLQRYIPQNGGFTWPGDYLRLEIVEMPKLKSINIKKTSLKQKI
NVQPVGIMPRKYLIEKHNIKVLKKKLSQAYSTQQLTKVVQEYKNLIQN
Ligand information
Ligand IDIHP
InChIInChI=1S/C6H18O24P6/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24)/t1-,2-,3-,4+,5-,6-
InChIKeyIMQLKJBTEOYOSI-GPIVLXJGSA-N
SMILES
SoftwareSMILES
CACTVS 3.385O[P](O)(=O)O[CH]1[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH]1O[P](O)(O)=O
ACDLabs 12.01
OpenEye OEToolkits 2.0.7		C1(C(C(C(C(C1OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O
CACTVS 3.385O[P](O)(=O)O[C@@H]1[C@H](O[P](O)(O)=O)[C@H](O[P](O)(O)=O)[C@@H](O[P](O)(O)=O)[C@H](O[P](O)(O)=O)[C@H]1O[P](O)(O)=O
FormulaC6 H18 O24 P6
NameINOSITOL HEXAKISPHOSPHATE;
MYO-INOSITOL HEXAKISPHOSPHATE;
INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE
ChEMBLCHEMBL1233511
DrugBankDB14981
ZINCZINC000169289809
PDB chain7xzi Chain A Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xzi Architecture of chloroplast TOC-TIC translocon supercomplex.
Resolution2.77 Å
Binding residue
(original residue number in PDB)		W1235 K1238 K1276 Y1359 K1457 K1464 S1690 K1692
Binding residue
(residue number reindexed from 1)		W990 K993 K1031 Y1059 K1157 K1164 S1342 K1344
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0009507 chloroplast
GO:0016020 membrane
GO:0031969 chloroplast membrane

View graph for
Cellular Component
External links
PDB RCSB:7xzi, PDBe:7xzi, PDBj:7xzi
PDBsum7xzi
PubMed36702157
UniProtP36495|YCF78_CHLRE Uncharacterized membrane protein ycf78 (Gene Name=ycf78)

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