Structure of PDB 7xv4 Chain A Binding Site BS01

Receptor Information
>7xv4 Chain A (length=117) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITPPRYRLLMSDGLNTL
SSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELEVLK
SAEAVGVKIGNPVPYNE
Ligand information
Receptor-Ligand Complex Structure
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PDB7xv4 Structural characterization of human RPA70N association with DNA damage response proteins.
Resolution1.6 Å
Binding residue
(original residue number in PDB)
R43 S54 M57 L87 K88 D89 R91 V93
Binding residue
(residue number reindexed from 1)
R40 S51 M54 L84 K85 D86 R88 V90
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:7xv4, PDBe:7xv4, PDBj:7xv4
PDBsum7xv4
PubMed37668474
UniProtP27694|RFA1_HUMAN Replication protein A 70 kDa DNA-binding subunit (Gene Name=RPA1)

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