Structure of PDB 7xsq Chain A Binding Site BS01 |
| >7xsq Chain A (length=1289) Species: 237368 (Candidatus Scalindua brodae)
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DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSF
LRKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFS
NFDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGT
YTGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAE
VIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHH
LWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVS
TRFRILGDTEYYSKAHDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPF
YFGVQQPSDSIPGKEKSLVINEHTSFNILLDKENRYRIPRSALRGALRRD
LRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIA
KNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEEN
DGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMRGKEK
ELLEMGESSLPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEVGSPL
LTADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIFR
TAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGNEFEK
LEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFSG
DHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMINK
TEPINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDIITHEEF
TEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFFNINGE
LMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSWKCASKTLGGKLDKAL
HPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNPERS
LTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQP
ERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLGKGK
PYGFGSVKIKIDSLHTFKINSNNDKIKRVPQSDIREYINKGYQKLIEWSG
NNSIQKGNVLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESK
GYIEGSDYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ |
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| PDB | 7xsq Target RNA activates the protease activity of Craspase to confer antiviral defense. |
| Resolution | 2.88 Å |
Binding residue
(original residue number in PDB) | E16 R19 W23 R37 F41 T45 F57 L62 R64 S91 F92 T94 P102 S103 F104 L105 R106 R108 G134 D137 K141 H143 Y149 H152 F153 N155 D157 I177 L178 N179 R180 V181 G186 K187 A188 D190 F192 K229 R380 Y389 S391 R472 S473 R476 R481 L495 L500 L514 R530 I531 A532 V540 L545 F546 G593 S596 A685 R728 I730 N760 E761 S765 H789 V790 I792 R794 A799 K804 F805 S854 P967 T969 S1001 R1004 R1008 I1021 T1422 T1423 L1459 E1460 P1462 R1463 Y1481 K1551 K1553 P1554 Y1645 Y1663 |
Binding residue
(residue number reindexed from 1) | E12 R15 W19 R33 F37 T41 F53 L58 R60 S87 F88 T90 P98 S99 F100 L101 R102 R104 G130 D133 K137 H139 Y145 H148 F149 N151 D153 I173 L174 N175 R176 V177 G182 K183 A184 D186 F188 K225 R352 Y361 S363 R440 S441 R444 R449 L463 L468 L482 R498 I499 A500 V508 L513 F514 G561 S564 A653 R696 I698 N728 E729 S733 H757 V758 I760 R762 A767 K772 F773 S822 P922 T924 S956 R959 R963 I976 T1019 T1020 L1056 E1057 P1059 R1060 Y1078 K1148 K1150 P1151 Y1242 Y1260 |
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| Enzyme Commision number |
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