Structure of PDB 7xs0 Chain A Binding Site BS01

Receptor Information

>7xs0 Chain A (length=376) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HHHHHSYHDSIKDSIKAVVNISTEKERMERALGSGVIISKDGYIVTNNHV
IDGADKIKVTIPGSNKEYSATLVGTDSESDLAVIRITKDNLPTIKFSDSN
DISVGDLVFAIGNPFGVGESVTQGIVSALNKSGIGINSYENFIQTDASIN
PGNSGGALIDSRGGLVGINTAIIGFAIPSNMVKDTVTQLIKTGKIERGYL
GVGLQDLSGDLDNKEGAVVISVEKDSPAKKAGILVWDLITEVNGKKVKNT
NELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAETISAQNGLQVEDLTQ
ETKRSSDDVQGVLVSQVNENSPAEQAGFRQGNIITKIEEVEVKSVADFNH
ALEKYKGKPKRFLVLDLNQGYRIILV

Ligand information

>7xs0 Chain B (length=3) Species: 469008 (Escherichia coli BL21(DE3)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

AAA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7xs0 Trimer structure of HtrA from Helicobacter pylori bound with a tripeptide
Resolution	2.59 Å
Binding residue (original residue number in PDB)	Y275 L276 G277 V278 L280 R334
Binding residue (residue number reindexed from 1)	Y199 L200 G201 V202 L204 R254

Enzymatic activity

Enzyme Commision number

3.4.21.107: peptidase Do.

Gene Ontology

	Molecular Function
GO:0004252	serine-type endopeptidase activity
GO:0008233	peptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:7xs0, PDBe:7xs0, PDBj:7xs0
PDBsum	7xs0
PubMed	37301353
UniProt	O25663

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