Structure of PDB 7xp0 Chain A Binding Site BS01

Receptor Information
>7xp0 Chain A (length=200) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GETLSEHVFRKIQSAIVSGEIAPGSKISEPELARTYGISRGPLREAIHRL
EGLRLLVRVPHVGARVVSLSHAELIELYEIRESLEGMACRLAAERMSQAE
IDELRRVLDTHEQQEGDYDFHYRIIQGSGNATLTRMLCGELYQLVRMYRI
QYSTTPNRPRQAFAEHHRILDAIADRDGELAELLMRRHISASRRNIERQL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xp0 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7xp0 PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa.
Resolution2.61 Å
Binding residue
(original residue number in PDB)		D143 H147 H192 H214
Binding residue
(residue number reindexed from 1)		D117 H121 H166 H188
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7xp0, PDBe:7xp0, PDBj:7xp0
PDBsum7xp0
PubMed36475801
UniProtQ9I5E1

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