Structure of PDB 7xjv Chain A Binding Site BS01

Receptor Information
>7xjv Chain A (length=507) Species: 580240 (Saccharomyces cerevisiae W303) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CWSYYEGLTPGWLNDFYDVNQITPNPAKDVIELVTRIKIFFNCLQQNIQR
LRDIEKKLFPYINFEKLETDESAFWHTTTRWNGEVYHASMLEFDPKNHQF
LRSKPINFDTGLSFWENWLHTVTQSGSKGIVISASDVQLNETIRLLKVLR
FIKNDYPIQIVHNADLSQDSMKSIIKYARSLDTAEYPAQELWFLNVHSLL
NPKYSKKFTTYSNKWLALTFSSFEIPILMDSDTVPFVSIKKFYELEEFQK
TGVLFFKDRVISDDLFESSELKILREIVYGCIGLDLEDESKIHEQVEDPV
VAQVLENMFIKKYKHHLESGLVILHKGKHLFSMLTSIALQFSPIAEYFHG
DKDFFWLGELLSNNRFTFHPVDASNIGQLGNVVSKEFYQICSVQLSHTDR
DGSLLWLNGGLNICKKTSWEYDYEHRQRLNDMFQNADELREYYASPVKLE
GIIIPDTSISGWINSGECFLFNYCTLFKEGEFGKLIKFKEDEKLRLSQIV
DIWNKDI
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7xjv Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7xjv Crystal Structure of Alpha-1,3-mannosyltransferase MNT2 from Saccharomyces cerevisiae, Mn/GDP-mannose form
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D237 D239 N419
Binding residue
(residue number reindexed from 1)		D230 D232 N408
Annotation score4
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0000030 mannosyltransferase activity
GO:0000033 alpha-1,3-mannosyltransferase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
GO:0006493 protein O-linked glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0000329 fungal-type vacuole membrane
GO:0005794 Golgi apparatus
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0071944 cell periphery

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xjv, PDBe:7xjv, PDBj:7xjv
PDBsum7xjv
PubMed
UniProtP53059|MNT2_YEAST Alpha-1,3-mannosyltransferase MNT2 (Gene Name=MNT2)

[Back to BioLiP]