Structure of PDB 7xhv Chain A Binding Site BS01

Receptor Information
>7xhv Chain A (length=177) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKERLARENHSEIERRRRNKMTAYITELSDMVPTCSAARKPDKLTILRMA
VSHMKSLRGPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPV
LNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSGSRRSFICRMRCGTSSVF
VVVHCTGYIKAWPPAGFCLVAIGRLQV
Ligand information
Receptor-Ligand Complex Structure
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PDB7xhv Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.
Resolution3.996 Å
Binding residue
(original residue number in PDB)		H94 R99 R102 D127 K128
Binding residue
(residue number reindexed from 1)		H10 R15 R18 D42 K43
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xhv, PDBe:7xhv, PDBj:7xhv
PDBsum7xhv
PubMed36343253
UniProtP53762|ARNT_MOUSE Aryl hydrocarbon receptor nuclear translocator (Gene Name=Arnt)

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