Structure of PDB 7x7l Chain A Binding Site BS01

Receptor Information

>7x7l Chain A (length=364) Species: 4577 (Zea mays)

FNPRSDRFHTLAFHHVELWCADAASAAGRFSFGLGAPLAARSDLSTGNSA
HASLLLRSGSLSFLFTAPYAHGADAATAALPSFSAAAARRFAADHGLAVR
AVALRVADAEDAFRASVAAGARPAFGPVDLGRGFRLAEVELYGDVVLRYV
SYPDGAAGEPFLPGFEGVASPGAADYGLSRFDHIVGNVPELAPAAAYFAG
FTGFHEFAEFTTGLNSMVLANNSENVLLPLNEPVHRSQIQTFLDHHGGPG
VQHMALASDDVLRTLREMQARSAMGGFEFMAPPTSDYYDGVRRRAGDVLT
EAQIKECQELGVLVDRDDQGVLLQIFTKPVGDRPTLFLEIIQRIGCMEYQ
KGGCGGFGKGNFSQ

Ligand information

• Ligand ID: CO
• InChI: InChI=1S/Co/q+2
• InChIKey: XLJKHNWPARRRJB-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Co+2]
  CACTVS 3.341: [Co++]
• Formula: Co
• Name: COBALT (II) ION
• DrugBank: DB14205
• PDB chain: 7x7l Chain A Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7x7l Structural insights of 4-Hydrophenylpyruvate dioxygenase inhibition by structurally diverse small molecules
• Resolution: 1.887 Å
• Binding residue (original residue number in PDB): H219 H301 E387
• Binding residue (residue number reindexed from 1): H183 H253 E339
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity
• GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
• GO:0046872 metal ion binding
• GO:0051213 dioxygenase activity

Biological Process

• GO:0006559 L-phenylalanine catabolic process
• GO:0006572 tyrosine catabolic process
• GO:0009072 aromatic amino acid metabolic process

External links

• PDB: RCSB:7x7l, PDBe:7x7l, PDBj:7x7l
• PDBsum: 7x7l
• UniProt: A0A1D6H1G0