Structure of PDB 7x6y Chain A Binding Site BS01

Receptor Information
>7x6y Chain A (length=169) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGF
SSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLNGGQY
WAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQE
RVFPLFSVCSTGTYLRIWP
Ligand information
>7x6y Chain B (length=7) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
CSGVTFQ
Receptor-Ligand Complex Structure
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PDB7x6y A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Resolution1.39 Å
Binding residue
(original residue number in PDB)
T45 N46 T47 R48 A73 F89 Q99 S162 C164
Binding residue
(residue number reindexed from 1)
T40 N41 T42 R43 A68 F84 Q94 S157 C159
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:7x6y, PDBe:7x6y, PDBj:7x6y
PDBsum7x6y
PubMed35982226
UniProtQ9C029|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)

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