Structure of PDB 7x5e Chain A Binding Site BS01

Receptor Information
>7x5e Chain A (length=99) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKR
VTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTV
Ligand information
Receptor-Ligand Complex Structure
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PDB7x5e Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
V34 R56 R57 Y64
Binding residue
(residue number reindexed from 1)
V12 R34 R35 Y42
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:7x5e, PDBe:7x5e, PDBj:7x5e
PDBsum7x5e
PubMed36454022
UniProtO15525|MAFG_HUMAN Transcription factor MafG (Gene Name=MAFG)

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