Structure of PDB 7wnu Chain A Binding Site BS01

Receptor Information
>7wnu Chain A (length=553) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPPGPLTSGGLRVTALGGINEIGRNMTVFEHLGRLLIIDCGVLFPGHDEP
GVDLILPDMRHVEDRLDDIEALVLTHGHEDHIGAIPFLLKLRPDIPVVGS
KFTLALVAEKCREYRITPVFVEVREGQSTRHGVFECEYFAVNHSTPDALA
IAVYTGAGTILHTGDIKFDQLPPDGRPTDLPGMSRLGDTGVDLLLCDSTN
AEIPGVGPSESEVGPTLHRLIRGADGRVIVACFASNVDRVQQIIDAAVAL
GRRVSFVGRSMVRNMRVARQLGFLRVADSDLIDIAAAETMAPDQVVLITT
GTQGEPMSALSRMSRGEHRSITLTAGDLIVLSSSLIPGNEEAVFGVIDAL
SKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRNVMPVHGTWRMLRA
NAKLAASTGVPQESILLAENGVSVDLVAGKASISGAVPVGKMFVDGLIAG
DVGDITLGERLILSSGFVAVTVVVRRGTGQPLAAPHLHSRGFSEDPKALE
PAVRKVEAELESLVAANVTDPIRIAQGVRRTVGKWVGETYRRQPMIVPTV
IEV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wnu Structural ans functional study of RNase J from Mycobacterium tuberculosis
Resolution3.2 Å
Binding residue
(original residue number in PDB)		I27 F49 H83 E84 E118 S240 R264 S265 R268 T305 E310 R317 E322 H323 I341 P342 G374 H375
Binding residue
(residue number reindexed from 1)		I22 F44 H78 E79 E113 S235 R259 S260 R263 T300 E305 R312 E317 H318 I336 P337 G369 H370
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.5.2.6: beta-lactamase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0004527 exonuclease activity
GO:0004534 5'-3' RNA exonuclease activity
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
GO:0046872 metal ion binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wnu, PDBe:7wnu, PDBj:7wnu
PDBsum7wnu
PubMed
UniProtP9WGZ9|RNJ_MYCTU Ribonuclease J (Gene Name=rnj)

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