Structure of PDB 7wku Chain A Binding Site BS01
Receptor Information
>7wku Chain A (length=304) Species:
1586324
(Porcine deltacoronavirus) [
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AGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGDQ
WTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPDY
KFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGYT
LKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYYT
DNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTNM
SYIMGLSQTARVPVERILNTIIQLTTNRDGACIMGSYDFECDWTPEMVYN
QAPI
Ligand information
>7wku Chain J (length=5) Species:
32630
(synthetic construct) [
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gAVLa
Receptor-Ligand Complex Structure
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PDB
7wku
The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
H41 F139 G142 C144 H162 H163 I164 E165 F166 N167 D186 E188 I190
Binding residue
(residue number reindexed from 1)
H41 F139 G142 C144 H162 H163 I164 E165 F166 N167 D186 E188 I190
Enzymatic activity
Enzyme Commision number
2.1.1.57
: methyltransferase cap1.
3.4.19.12
: ubiquitinyl hydrolase 1.
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
Gene Ontology
Molecular Function
GO:0008233
peptidase activity
Biological Process
GO:0019082
viral protein processing
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Molecular Function
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Biological Process
External links
PDB
RCSB:7wku
,
PDBe:7wku
,
PDBj:7wku
PDBsum
7wku
PubMed
35336895
UniProt
A0A140ESF0
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