Structure of PDB 7wal Chain A Binding Site BS01

Receptor Information
>7wal Chain A (length=484) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMANAVIGNVVTRFPPEPSGYLHVGHAKAAFLNNYYAQMYEGKMLLRFDD
TNPVKYEKSIIEDLENLGLKYEKISYSSDHFDLLEKYCIDMIKMNKAYAD
DTGVEDMRNQRGEGIESINRNNSIEKNLELFNEMRKGTEIGQKNCIRAKI
NMQSKNKCMRDPVMYRCIVDVPKYKCYPTYDFACPIIDSIEGVTHALRTN
EDRIEQYNWFISTLNLRKVYIYEFSRLAFVKTVMSKRKLKWFVENNVVDS
WVDPRFPTIKGILRRGLTKEALFQFILEQNLMQWDKLWSINKQIIDPIIP
RYAAVDKNSSILLILTDLTDQVIQKERDLHMKNKSLGTCNMYYNNKYLIE
LEDAQTLLENEEITLIKLGNIIIKNIEKENGKIKQINALSNFHTTKKKIH
WLPYLPQQLITCTLYEYDHLITVDKDWTNFINFNSKHETLVYAEPSISSL
KVSDKFQFERRGYFILDKIDPHHHLHLIKIPDGK
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain7wal Chain A Residue 1007 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7wal Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Resolution2.29 Å
Binding residue
(original residue number in PDB)		D800 H806
Binding residue
(residue number reindexed from 1)		D470 H476
Annotation score1
Enzymatic activity
Enzyme Commision number 6.1.1.17: glutamate--tRNA ligase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wal, PDBe:7wal, PDBj:7wal
PDBsum7wal
PubMed36370911
UniProtQ8IDK7

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