Structure of PDB 7wa0 Chain A Binding Site BS01
Receptor Information
>7wa0 Chain A (length=223) Species:
9913
(Bos taurus) [
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IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRL
GEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRV
ASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKS
AYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQK
NKPGVYTKVCNYVSWIKQTIASN
Ligand information
Ligand ID
CA
InChI
InChI=1S/Ca/q+2
InChIKey
BHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
Formula
Ca
Name
CALCIUM ION
ChEMBL
DrugBank
DB14577
ZINC
PDB chain
7wa0 Chain A Residue 303 [
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Receptor-Ligand Complex Structure
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PDB
7wa0
In situ crystal data-collection and ligand-screening system at SPring-8.
Resolution
1.77 Å
Binding residue
(original residue number in PDB)
E75 N77 V80 E85
Binding residue
(residue number reindexed from 1)
E52 N54 V57 E62
Annotation score
4
Enzymatic activity
Enzyme Commision number
3.4.21.4
: trypsin.
Gene Ontology
Molecular Function
GO:0004175
endopeptidase activity
GO:0004252
serine-type endopeptidase activity
GO:0005515
protein binding
GO:0008236
serine-type peptidase activity
GO:0046872
metal ion binding
GO:0097655
serpin family protein binding
Biological Process
GO:0006508
proteolysis
GO:0007586
digestion
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
GO:0097180
serine protease inhibitor complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:7wa0
,
PDBe:7wa0
,
PDBj:7wa0
PDBsum
7wa0
PubMed
35647681
UniProt
P00760
|TRY1_BOVIN Serine protease 1 (Gene Name=PRSS1)
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