Structure of PDB 7w8d Chain A Binding Site BS01

Receptor Information

>7w8d Chain A (length=156) Species: 1299 (Deinococcus radiodurans)

MRVLGIDPGLANLGLGLVEGDVRRAKHLYHVCLTTESAWLMPRRLQYLHE
ELTRLLTEYRPDAVAIEDQILRRQADVAFKVGQAFGVVQLACAQAGVPIH
AYGPMQVKKSLVGTGRADKEQVIYMVKASLGIRELFNNHAADALALALTH
LAHAPM

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7w8d Chain A Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7w8d Biochemical and Structural Study of RuvC and YqgF from Deinococcus radiodurans.
• Resolution: 2.75016 Å
• Binding residue (original residue number in PDB): D7 E67
• Binding residue (residue number reindexed from 1): D7 E67
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 3.1.21.10: crossover junction endodeoxyribonuclease.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0003676 nucleic acid binding
• GO:0003677 DNA binding
• GO:0004519 endonuclease activity
• GO:0004520 DNA endonuclease activity
• GO:0008821 crossover junction DNA endonuclease activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006281 DNA repair
• GO:0006310 DNA recombination

Cellular Component

• GO:0005737 cytoplasm
• GO:0048476 Holliday junction resolvase complex

External links

• PDB: RCSB:7w8d, PDBe:7w8d, PDBj:7w8d
• PDBsum: 7w8d
• PubMed: 36000732
• UniProt: Q9RX75|RUVC_DEIRA Crossover junction endodeoxyribonuclease RuvC (Gene Name=ruvC)