Structure of PDB 7w7l Chain A Binding Site BS01

Receptor Information
>7w7l Chain A (length=294) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETADGPYLVIVEQPKQRGFRFRYGCEGPSHGGLPGASSEKGRKTYPTVKI
CNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGICAVSVGPKDMTAQ
FNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKELK
KVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISR
MDKTAGSVRGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVH
KQYAIVFRTPPYHKMKIERPVTVFLQLKRKRGGDVSDSKQFTYY
Ligand information
Receptor-Ligand Complex Structure
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PDB7w7l Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R52 Y55 C57 T142
Binding residue
(residue number reindexed from 1)		R20 Y23 C25 T110
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w7l, PDBe:7w7l, PDBj:7w7l
PDBsum7w7l
PubMed36779700
UniProtQ00653|NFKB2_HUMAN Nuclear factor NF-kappa-B p100 subunit (Gene Name=NFKB2)

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