Structure of PDB 7w6j Chain A Binding Site BS01

Receptor Information
>7w6j Chain A (length=177) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVD
EMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS
GYGQGDVLGFYINLPESSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKS
CTVSINFGPCFKYPPKDLTYRPMSDMG
Ligand information
>7w6j Chain F (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DFKELDENVEYEERESEFDI
Receptor-Ligand Complex Structure
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PDB7w6j Structural basis for product specificities of MLL family methyltransferases.
Resolution2.68 Å
Binding residue
(original residue number in PDB)		R323 L350
Binding residue
(residue number reindexed from 1)		R39 L66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:7w6j, PDBe:7w6j, PDBj:7w6j
PDBsum7w6j
PubMed36108631
UniProtQ9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (Gene Name=ASH2L)

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