Structure of PDB 7w5e Chain A Binding Site BS01

Receptor Information
>7w5e Chain A (length=125) Species: 1969 (Streptomyces chartreusis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMAVELNHTIVLVKDKDASATFMADLLGLPKPKEMGPFAVLQLANDVSI
LFMDFRGEGDIVPGHCAFLISDEEFDQIFGRIREGGIEHWADQYHEPGIN
DGGRGVYFEDPSGHNMEIMTRPYGS
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain7w5e Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7w5e Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		H63 Y109 E119
Binding residue
(residue number reindexed from 1)		H65 Y107 E117
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004462 lactoylglutathione lyase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7w5e, PDBe:7w5e, PDBj:7w5e
PDBsum7w5e
PubMed35415958
UniProtQ4R0L3

[Back to BioLiP]