Structure of PDB 7w2i Chain A Binding Site BS01

Receptor Information

>7w2i Chain A (length=183) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IDITGDWTVAVYCAASPTHAELLELAAEVGAAIAGRGWTLVWGGGHVSAM
GAVASAARACGGWTVGVIPKMLVYRELADHDADELIVTDTMWERKQIMED
RSDAFIVLPGGVGTLDELFDAWTDGYLGTHDKPIVMVDPWGHFDGLRAWL
NGLLDTGYVSPTAMERLVVVDNVKDALRACAPS

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

7w2i Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7w2i Crystal structure of the cytokinin-producing enzyme "lonely guy" (LOG) from Mycobacterium tuberculosis.
Resolution	1.8 Å
Binding residue (original residue number in PDB)	D124 D128
Binding residue (residue number reindexed from 1)	D120 D124
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.2.2.n1: cytokinin riboside 5'-monophosphate phosphoribohydrolase.

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0102682	cytokinin riboside 5'-monophosphate phosphoribohydrolase activity

	Biological Process
GO:0009691	cytokinin biosynthetic process

	Cellular Component
GO:0005829	cytosol

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External links

PDB	RCSB:7w2i, PDBe:7w2i, PDBj:7w2i
PDBsum	7w2i
PubMed	35158209
UniProt	O05306\|LOGH_MYCTU Cytokinin riboside 5'-monophosphate phosphoribohydrolase (Gene Name=log)

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