Structure of PDB 7w0q Chain A Binding Site BS01

Receptor Information
>7w0q Chain A (length=173) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA
SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLN
GGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRV
NFQERVFPLFSVCSTGTYLRIWP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7w0q A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Resolution1.1 Å
Binding residue
(original residue number in PDB)
N383 T384 R385 A410 L423 F426 Q436 S499 C501 S502
Binding residue
(residue number reindexed from 1)
N45 T46 R47 A72 L85 F88 Q98 S161 C163 S164
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:7w0q, PDBe:7w0q, PDBj:7w0q
PDBsum7w0q
PubMed35982226
UniProtQ9C029|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)

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