Structure of PDB 7vze Chain A Binding Site BS01
Receptor Information
>7vze Chain A (length=89) Species:
9606
(Homo sapiens) [
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LVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGD
QVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRP
Ligand information
>7vze Chain E (length=7) Species:
333760
(Human papillomavirus 16) [
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TRRETQL
Receptor-Ligand Complex Structure
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PDB
7vze
Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein.
Resolution
2.882 Å
Binding residue
(original residue number in PDB)
R527 F528 G529 F530 N531 V532 K533 Q538 H579 D580
Binding residue
(residue number reindexed from 1)
R13 F14 G15 F16 N17 V18 K19 Q24 H65 D66
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:7vze
,
PDBe:7vze
,
PDBj:7vze
PDBsum
7vze
PubMed
35089587
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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