Structure of PDB 7vyx Chain A Binding Site BS01

Receptor Information
>7vyx Chain A (length=1211) Species: 2565572 (Parasutterella muris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLHLISAKASRKYRRTIACLSDTAKKDLERRKQSGAADPAQELSCLKTIK
FKLEVPEGSKLPSFDRISQIYNALETIEKGSLSYLLFALILSGFRIFPNS
SAAKTFASSSCYKNDQFASQIKEIFGEMVKNFIPSELESILKKGRRKNNK
DWTEENIKRVLNSEFGRKNSEGSSALFDSFLSKFSQELFRKFDSWNEVNK
KYLEAAELLDSMLASYGPFDSVCKMIGDSDSRNSLPDKSTIAFTNNAEIT
VDIESSVMPYMAIAALLREYRQSKSKAAPVAYVQSHLTTTNGNGLSWFFK
FGLDLIRKAPVSSGSKSLQELFSVPDDKLDGLKFIKEACEALPEASLLCG
EKGELLGYQDFRTSFAGHIDSWVANYVNRLFELIELVNQSHSLELFEGLV
KNVRQTLKKLAGIDISSSPNEQDIKEFYAFSDVLNRLGSIRNQIENAVKK
LKKLPKLNGLGGGVPKQQELLDKALESVKQIRHYQRIDFERVIQWAVNEH
CLETVPKFLVDAEKKKINKESSTDFAAKENAVRFLLEGIGAAARGKTDSV
SKAAYNWFVVNNFLAKKDLNRYFINCQGCIYKPPYSKRRSLAFALRSDNK
DTIEVVWEKFETFYKEISKEIEKFNIFSQEFQTFLHLENLRMKLLLRRIQ
KPIPAEIAFFSLPQEYYDSLPPNVAFLNQEITPSEYITQFNLYSSFLNGN
LILLRRSRSYLRAKFSWVGNSKLIYAAKEARLWKIPNAYWKSDEWKMILD
SNVLVFDKAGNVLPAPTLKKVCEREGDLRLFYPLLRQLPHDWCYRNPFVK
SVGREKNVIEVNKEGEPKVASALPGSLFRLIGPAPFKSLLDDCFFNPLDK
DLRECMLIVDQEISQKVEAQKVEASLESCTYSIAVPIRYHLEEPKVSNQF
ENVLAIAQGEAGLAYAVFSLKSIGEAETKPIAVGTIRIPSIRRLIHSVST
YRKKKQRLQNFKQNYDSTAFIMRENVTGDVCAKIVGLMKEFNAFPVLEYD
VSRQLSAVYKAVNSHFLYFKEPGRDALRKQLWYGGDSWTIDGIEIVTRER
KEDGKEGVEKIVPLKVFPGRSVSARFTSKTCSCCGRNVFDWLFTEKKAFN
VNSKGELTTADGVIQLFEADRSKGPKFYARRKERTPLTKPIAKGSYSLEE
IERRVRTNLRRAPKSKQSRDTSQSQYFCVYKDCALHFSGMQADENAAINI
GRRFLTALRKN
Ligand information
>7vyx Chain C (length=103) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggaaacucccgacuuccucaggaugaaguuucuuuauccauaccuuggug
ccgggacgccgcggcgccuuccaggaaggguuuauaaggcaacaucgaac
aua
..<<<.<<<<<.<.<.....<<..<........>..>>....(((..>.>
.>>>>><<<<..>>>><<<<<<.>>>>>>.>>>...)))...........
...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7vyx Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system
Resolution3.2 Å
Binding residue
(original residue number in PDB)		H7 H9 S12 A13 K14 R20 L52 K53 T54 K56 K58 R391 P515 K516 N518 G519 N630 R631 N635 R774 K776 R793 W795 K796 P798 A800 Y801 S804 Q849 P851 H852 R891 I893 G894 P895 A896 P897 F898 S900 M918 R1005 R1019 K1024 N1037 D1041 R1071 Q1098 R1204 S1238 Q1240 S1241 R1242
Binding residue
(residue number reindexed from 1)		H1 H3 S6 A7 K8 R14 L46 K47 T48 K50 K52 R379 P455 K456 N458 G459 N570 R571 N575 R712 K714 R731 W733 K734 P736 A738 Y739 S742 Q787 P789 H790 R829 I831 G832 P833 A834 P835 F836 S838 M856 R943 R957 K962 N975 D979 R1003 Q1030 R1131 S1165 Q1167 S1168 R1169
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