Structure of PDB 7vox Chain A Binding Site BS01

Receptor Information
>7vox Chain A (length=85) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNS
IRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGN
Ligand information
Receptor-Ligand Complex Structure
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PDB7vox FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		S174 Y175 R213 N216 S217 H220
Binding residue
(residue number reindexed from 1)		S7 Y8 R46 N49 S50 H53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7vox, PDBe:7vox, PDBj:7vox
PDBsum7vox
PubMed35920317
UniProtP55317|FOXA1_HUMAN Hepatocyte nuclear factor 3-alpha (Gene Name=FOXA1)

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