Structure of PDB 7vlz Chain A Binding Site BS01

Receptor Information

>7vlz Chain A (length=532) Species: 1300145 (Vibrio harveyi VHJR7)

CDVEAFTSNSSNDVLNAIKTQGASCVNALFSAESRIQEAAFESGHMYNIA
KHTTDLAKAYAGGGSDELEALFLYLRAGYYAEFYNSKVSFLSWVTPAVKE
AVDAFVNNANFYENSDPHGKVLSEVIITMDSAGLQHAYLPQVTQWLTRWD
SQYAQNWYMRNAVNGVFTILFGGQWNEQFVQTIGNQTELAKALGDFALRS
SAIGASDEFMAANAGRELGRLTKYSGSASSTVKSKLTEIFAQYEMYGRGD
AIWLGAADTVSYYADCSDYGICNFESQLKGLVLSQSYTCSPTIRILSQNM
TQDQHVAACSKMGYEEGYFHTSLETGRQPVADDYNTQLQVNIFDSSDDYG
KYAGPIFNISTNNGGMYLEGDPATPGNIPNFVAYEAPYANPDHFVWNLEH
EYVHYLDGRFDLYGGFGHPTERIVWWSEGIAEYVSKENDNQAAIDTIKDG
STFTLSEIFETSYDGFDVDRIYRWGYLAVRFMFERHKDDVNQMLIETRQG
NWANYKATINQWAILYQSEFEQWQQALVLEHH

Ligand information

>7vlz Chain B (length=14) Species: 1300145 (Vibrio harveyi VHJR7)

EPSQQVTEIYQHHA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7vlz Crystal structure of the collagenase unit of a Vibrio collagenase from Vibrio harveyi VHJR7
• Resolution: 1.6 Å
• Binding residue (original residue number in PDB): W234 R237 N238 F248 F286 N290 R293 S423 N439 N440 G441 G442 Y461 Y465 W473 H477 E478 H481 E505 V545 Y549
• Binding residue (residue number reindexed from 1): W157 R160 N161 F171 F209 N213 R216 S346 N362 N363 G364 G365 Y384 Y388 W396 H400 E401 H404 E428 V468 Y472

Enzymatic activity

• Enzyme Commision number: 3.4.24.3: microbial collagenase.

Gene Ontology

Molecular Function

• GO:0004222 metalloendopeptidase activity
• GO:0008270 zinc ion binding

Biological Process

• GO:0006508 proteolysis

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:7vlz, PDBe:7vlz, PDBj:7vlz
• PDBsum: 7vlz
• UniProt: A0A8B3DGT3