Structure of PDB 7vdt Chain A Binding Site BS01

Receptor Information
>7vdt Chain A (length=617) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLIDQKKDKRLAYLLQQTDEYYAVAHAVTERVDKQSALMVNGVLKQYQIK
GLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIV
PLSTLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVPQLRSGKFNVLLTTY
EYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLT
GTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRH
MQAKGVLLTDGSGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGG
IVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAY
RGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSA
DTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAA
KYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDET
VNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWIIKEK
MFGRGSRHRKEVDYSDS
Ligand information
>7vdt Chain I (length=135) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggtgccgaggccgctcaattggtcgtagacagctctagcaccgcttaaac
gcacgtacgcgctgtcccccgcgttttaaccgccaaggggattactccct
agtctccaggcacgtgtcagatatatacatcctga
Receptor-Ligand Complex Structure
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PDB7vdt Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R885 K887 C891 K892 H900 W1178
Binding residue
(residue number reindexed from 1)		R175 K177 C181 K182 H190 W460
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0042393 histone binding
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7vdt, PDBe:7vdt, PDBj:7vdt
PDBsum7vdt
PubMed35477757
UniProtP51532|SMCA4_HUMAN Transcription activator BRG1 (Gene Name=SMARCA4)

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