Structure of PDB 7vcp Chain A Binding Site BS01

Receptor Information
>7vcp Chain A (length=490) Species: 1267021 (Frischella perrara) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMKNLIAEANQAVEQFAGQVKARYYPAYHIAAKSGWINDPNGLIYFNNQ
YHVFFQHHPYNEQWGKIHWGHVVSDDLVHWRNLPIALAPSQEYDKDGCFS
GCAIDDNGVLTLIYTGHVVLKEAGDKSVFKQVQCLATSKDGIHFEKQGVI
VTPPEGIMHFRDPKVWRQDDQWYMVVGVNDHDNTGQVWLYHSQDLYHWQF
VQVLAKMADPNVYMLECPDFFPLGDKYVLTCSPQGMKANGYHYRNRYQSG
YIVGDWQPGSAFTITQDFTELDFGHDYYAPQTLISHDQRRIVIAWMDMWD
SVMPSQADKWAGVLTLPRTLMLSSNNKLLINPITELKSLRGIQKKITSIN
LSNAIQDLQLDSMQCELILKIDLTNSDAERAGIALSASPDGKQSTLLYVD
NQAQRVILDRTYSGEGMVGYRSVALPADKFLTLHIFIDHSSVEVFVNEGQ
ATLTSRIYPTSEKRTLFLFAENGALRVEQLDYWQIKNMRG
Ligand information
Ligand IDFRU
InChIInChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
InChIKeyRFSUNEUAIZKAJO-ARQDHWQXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OC1C(O)C(OC1(O)CO)CO
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O
CACTVS 3.341OC[CH]1O[C](O)(CO)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)(CO)O)O)O)O
CACTVS 3.341OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
FormulaC6 H12 O6
Namebeta-D-fructofuranose;
beta-D-fructose;
D-fructose;
fructose
ChEMBLCHEMBL604608
DrugBank
ZINCZINC000001529270
PDB chain7vcp Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7vcp Enzymatic and structural characterization of beta-fructofuranosidase from the honeybee gut bacterium Frischella perrara.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		N37 D38 Q54 F97 S98 R159 D160 E214 Y276 W297
Binding residue
(residue number reindexed from 1)		N39 D40 Q56 F99 S100 R161 D162 E216 Y278 W299
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.26: beta-fructofuranosidase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004564 beta-fructofuranosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005985 sucrose metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7vcp, PDBe:7vcp, PDBj:7vcp
PDBsum7vcp
PubMed35267055
UniProtA0A0A7S0J1

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