Structure of PDB 7vcf Chain A Binding Site BS01

Receptor Information
>7vcf Chain A (length=1496) Species: 3055 (Chlamydomonas reinhardtii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLVTSVKDYVEITHKLIEIEPLKNYTEFGAVFTYFIFSIGEFFKNFFSFS
FLNNIWSIPIIIPDIASAMISEVSVLDGYFHNAFTFLETPSLVIFEKFVI
GIINSLFLILPTSTSHLITLRRFVMQGLEAGYMAGLGTLAGNFLWLASII
LGWRFFVIPWLSLDIFRYLLGFVLLVKYIWDSSKERRMALEDLSKWKIFL
LNFLLALTEQSCIYPFISNLSFGPDASILEGFPVDNYPQFLLIHGAYLLG
ILFGSFSLLQFTCWFWENPAFSIYLWITTKSSLKISTSSYYKILNFTFLY
ATMLCAIASIPYYGLDYTITNPIGLVPQDRILNQKKSQSDPDKLITETAF
LNLNPTDKNSRIRDGVHARRERWKQRLIKYQAFDASTYDQGVYDFLTIED
LNYGFDRFWLRRKMRNHQGPRVEFFRILFEQFYHPNFHDRGLVLTNTQAT
LLPTDLQTKRTIKPGLIYTNSALRKFVRNVNTRLNLKLLNSKQFIYSKRW
KSIFSKIQPLQNGTTRKSYQLFRNVAKQILVTPDAKSLKLITINQKLSLK
ERKLLELRTQYNNNTLVRPLNVYLQKEEAFKRKLRYYGTMPMRKLTVGNQ
APYFKALMKRGFYYYKPTLRWRKTLYVASLRRGFRKKSRKQRILVMSLIT
KPTHSYTVLGKRASRYRHQIYKDVLQHWYYTPFNRLLMKFDVDAFINRQP
KSHFLTKNEERALHIRRFLLSEHYDTLRWYTYMQHYKTMKTNIGGTKSFA
NRAYNQQFQGTFKKIRHLFAITPKQGDFYTLKFDQPLYNDNKLKDNLYFH
EELLTDYYNGTNLQTNQTSNISVNSTTNFVYSELFVKLIKECKKRIHDQT
FLKNYITHRIEKREQLNQEQTKELNKRLEKLKVWLNSDKPDKVLTTAMQK
AVNESISLSGIMPSDKIKTTYGNLTNAYTIKTENAILTKLNVINQLTLRV
KTDKDLQWWRTKQRVITKRKSARKRDRFKKQIAVVNKKLRKKISSKGRRY
RSLSLARYLTATRKPRLVGLDNLTKIDNITTLQGAFITKEEKQDSLNLTI
QRKQELTNSLKKSQIKKRSRHSWKKRSRHQFSRNHYKYRKRHTHGNGKLR
VMNKKLKKFKATNELRQWWWNSFLPRYLSNLQKSFDITSMTTTLPFYAGW
DESLKKFVVTNRLLSRRDAGLSVNNNPQEINFTNPPIQGLNEGSFLYWQT
EMPFNSYNIDQFITTNQSFYAPLGWRRFEFRHSILKTWVNNKTLIISLKN
LQPLKSSQQKQNQIKTKKLVARRIKKRYKLLKQMPNQLMYSPTGPLLTEV
LPSHYISVFDQQYRLPRNRYLKRNPLKTLKKTTLLALMDSSKQTNGVNKE
FTLRKRVKPRRKYHRKRFIKKDGLIFPRRTKFNTNDDLRWRPSSQLRRRE
FQQVLKPLQRYIPQNGGFTWPGDYLRLEIVEMPKLKSINIKKTSLKQKIN
VQPVGIMPRKYLIEKHNIKVLKKKLSQAYSTQQLTKVVQEYKNLIQ
Ligand information
Ligand IDIHP
InChIInChI=1S/C6H18O24P6/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24)/t1-,2-,3-,4+,5-,6-
InChIKeyIMQLKJBTEOYOSI-GPIVLXJGSA-N
SMILES
SoftwareSMILES
CACTVS 3.385O[P](O)(=O)O[CH]1[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH]1O[P](O)(O)=O
ACDLabs 12.01
OpenEye OEToolkits 2.0.7		C1(C(C(C(C(C1OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O
CACTVS 3.385O[P](O)(=O)O[C@@H]1[C@H](O[P](O)(O)=O)[C@H](O[P](O)(O)=O)[C@@H](O[P](O)(O)=O)[C@H](O[P](O)(O)=O)[C@H]1O[P](O)(O)=O
FormulaC6 H18 O24 P6
NameINOSITOL HEXAKISPHOSPHATE;
MYO-INOSITOL HEXAKISPHOSPHATE;
INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE
ChEMBLCHEMBL1233511
DrugBankDB14981
ZINCZINC000169289809
PDB chain7vcf Chain A Residue 2005 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7vcf Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		W1235 K1238 Y1359 K1457 K1464 S1690 L1691 K1692
Binding residue
(residue number reindexed from 1)		W959 K962 Y1000 K1098 K1105 S1247 L1248 K1249
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0009507 chloroplast
GO:0016020 membrane
GO:0031969 chloroplast membrane

View graph for
Cellular Component
External links
PDB RCSB:7vcf, PDBe:7vcf, PDBj:7vcf
PDBsum7vcf
PubMed36413996
UniProtP36495|YCF78_CHLRE Uncharacterized membrane protein ycf78 (Gene Name=ycf78)

[Back to BioLiP]