Structure of PDB 7v1a Chain A Binding Site BS01

Receptor Information
>7v1a Chain A (length=300) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APGQKECDNALRQLETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEA
MTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQA
GQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTSALC
NSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRA
QCRAATAPLLEAVDNLSAFASNPEFSSVPAQISPEGRAAMEPIVISAKTM
LESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7v1a Inhibition of talin-induced integrin activation by a double-hit stapled peptide.
Resolution1.845 Å
Binding residue
(original residue number in PDB)
L1492 A1495 T1496 A1499 S1503 C1506 V1526 K1530
Binding residue
(residue number reindexed from 1)
L136 A139 T140 A143 S147 C150 V170 K174
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:7v1a, PDBe:7v1a, PDBj:7v1a
PDBsum7v1a
PubMed37369205
UniProtP26039|TLN1_MOUSE Talin-1 (Gene Name=Tln1)

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