Structure of PDB 7v1a Chain A Binding Site BS01
Receptor Information
>7v1a Chain A (length=300) Species:
10090
(Mus musculus) [
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APGQKECDNALRQLETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEA
MTGISQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQA
GQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTSALC
NSCRLASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRA
QCRAATAPLLEAVDNLSAFASNPEFSSVPAQISPEGRAAMEPIVISAKTM
LESAGGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAP
Ligand information
>7v1a Chain B (length=19) Species:
10090
(Mus musculus) [
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DIDQMFSTLLGEKDLLKQS
Receptor-Ligand Complex Structure
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PDB
7v1a
Inhibition of talin-induced integrin activation by a double-hit stapled peptide.
Resolution
1.845 Å
Binding residue
(original residue number in PDB)
L1492 A1495 T1496 A1499 S1503 C1506 V1526 K1530
Binding residue
(residue number reindexed from 1)
L136 A139 T140 A143 S147 C150 V170 K174
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003779
actin binding
View graph for
Molecular Function
External links
PDB
RCSB:7v1a
,
PDBe:7v1a
,
PDBj:7v1a
PDBsum
7v1a
PubMed
37369205
UniProt
P26039
|TLN1_MOUSE Talin-1 (Gene Name=Tln1)
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