Structure of PDB 7v0f Chain A Binding Site BS01

Receptor Information
>7v0f Chain A (length=182) Species: 400667 (Acinetobacter baumannii ATCC 17978) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMLIRKLFKFENAHVVRNCTSDRCKRSIHGHSYKVELLLKASKLDHGQMV
YDFGLLKGVIKDLFDSFDHAICFWEKDDPQYIDACKTFSARWISLPVSPS
AEQFSRIFFYLAQQVLQSDVEVYSVIVHETDTGYAQSFLEDIQNEQMGLL
NLEGIIFSEQVQSEWADPNMYENLKQGIKFHN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7v0f Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7v0f Metal retention and replacement in QueD2 protect queuosine-tRNA biosynthesis in metal-starved Acinetobacter baumannii.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		H28 H30
Binding residue
(residue number reindexed from 1)		H29 H31
Annotation score1
Enzymatic activity
Enzyme Commision number 4.1.2.50: 6-carboxytetrahydropterin synthase.
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0070497 6-carboxy-5,6,7,8-tetrahydropterin synthase activity

View graph for
Molecular Function
External links
PDB RCSB:7v0f, PDBe:7v0f, PDBj:7v0f
PDBsum7v0f
PubMed36442121
UniProtA0A081GYS3

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