Structure of PDB 7uwo Chain A Binding Site BS01

Receptor Information
>7uwo Chain A (length=504) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRT
MQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSV
LFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCL
QILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCS
SNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGL
LGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTV
LRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPP
SHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRF
VEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENI
QRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLF
RMSE
Ligand information
>7uwo Chain B (length=16) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PAVMECYEAAFICHYV
Receptor-Ligand Complex Structure
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PDB7uwo De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Resolution2.75 Å
Binding residue
(original residue number in PDB)		R515 H578 I579 R582 R612 V613 C619 E620 T653 Y654 A656 A657 R661
Binding residue
(residue number reindexed from 1)		R364 H418 I419 R422 R452 V453 C459 E460 T493 Y494 A496 A497 R501
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

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Molecular Function
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Biological Process
External links
PDB RCSB:7uwo, PDBe:7uwo, PDBj:7uwo
PDBsum7uwo
PubMed36534810
UniProtP35222|CTNB1_HUMAN Catenin beta-1 (Gene Name=CTNNB1)

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