Structure of PDB 7uwi Chain A Binding Site BS01

Receptor Information
>7uwi Chain A (length=505) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVS
AIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGS
PVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI
TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKV
LSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE
GMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEA
LVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVK
LLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQD
TQVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIE
NIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAV
LFRMS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7uwi De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Resolution2.32 Å
Binding residue
(original residue number in PDB)		F253 Y254 T257 H260 N261 N290 K292 I296 D299 K335 R376
Binding residue
(residue number reindexed from 1)		F107 Y108 T111 H114 N115 N144 K146 I150 D153 K189 R230
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

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Molecular Function
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Biological Process
External links
PDB RCSB:7uwi, PDBe:7uwi, PDBj:7uwi
PDBsum7uwi
PubMed36534810
UniProtP35222|CTNB1_HUMAN Catenin beta-1 (Gene Name=CTNNB1)

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