Structure of PDB 7utt Chain A Binding Site BS01
Receptor Information
>7utt Chain A (length=351) Species:
10090
(Mus musculus) [
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KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTG
SYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKNPLSHFLEGE
VLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEIS
VDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDG
NSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLL
EQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAF
FLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD
K
Ligand information
>7utt Chain E (length=18) [
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atctgtacatgtacagat
Receptor-Ligand Complex Structure
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PDB
7utt
Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination
Resolution
2.04 Å
Binding residue
(original residue number in PDB)
R158 L159 K160 R161 H203 E386 K395
Binding residue
(residue number reindexed from 1)
R10 L11 K12 R13 H55 E231 K240
Enzymatic activity
Enzyme Commision number
2.7.7.86
: cyclic GMP-AMP synthase.
External links
PDB
RCSB:7utt
,
PDBe:7utt
,
PDBj:7utt
PDBsum
7utt
PubMed
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
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