Structure of PDB 7usf Chain A Binding Site BS01

Receptor Information
>7usf Chain A (length=265) Species: 11757 (Mouse mammary tumor virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALESAQESHALHHQNAAALRFQFHITREQAREIVKLCPNCPDWGHAPQLG
VNPRGLKPRVLWQMDVTHVSEFGKLKYVHVTVDTYSHFTFATARTGEATK
DVLQHLAQSFAYMGIPQKIKTDNAPAYVSRSIQEFLARWKISHVTGIPYN
PQGQAIVERTHQNIKAQLNKLQKAGKYYTPHHLLAHALFVLNHVNMDNQG
HTAAERHWGPISADPKPMVMWKDLLTGSWKGPDVLITAGRGYACVFPQDA
ESPIWVPDRFIRPFT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7usf B-to-A transition in target DNA during retroviral integration.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		Q48 G50 V51 R54 H87 T145 G146 I147 Q152 A155 R159 N163 R240
Binding residue
(residue number reindexed from 1)		Q48 G50 V51 R54 H87 T145 G146 I147 Q152 A155 R159 N163 R240
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7usf, PDBe:7usf, PDBj:7usf
PDBsum7usf
PubMed35947647
UniProtP03365|POL_MMTVB Gag-Pro-Pol polyprotein (Gene Name=gag-pro-pol)

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