Structure of PDB 7und Chain A Binding Site BS01

Receptor Information
>7und Chain A (length=1426) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMD
PRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRC
VCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNGGCGRYQ
PRIRRSGLELYAEWKKKILLSPERVHEIFKRISDEECFVLGMEPRYARPE
WMIVTVLPVPPLSVRPAVVMRNQDDLTHKLADIVKINNQLRRNEQNGAAA
HVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRV
RGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNID
RLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHM
CDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDE
MNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTK
RDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHI
NCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAG
SLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQ
DIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARD
KTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPF
GFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDT
AVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGES
VEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQN
ELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRL
PSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLC
SRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPAT
QMTKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRL
EHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVSPWLLRVELDRKHMTD
RKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNDDDVFLRCIE
SNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETD
GVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFD
GSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVL
MEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMGATPA
YGAWSPSVGSGMTPGAAGFSPSAASD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7und Structural basis of nucleosome retention during transcription elongation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		F431 R460 Q461 D495 D497 D499
Binding residue
(residue number reindexed from 1)		F381 R410 Q411 D445 D447 D449
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0031981 nuclear lumen
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7und, PDBe:7und, PDBj:7und
PDBsum7und
PubMed35709268
UniProtA0A7M4DUC2

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