Structure of PDB 7uih Chain A Binding Site BS01

Receptor Information
>7uih Chain A (length=574) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSED
VEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYSARMNLASSFV
NGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLT
QIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDFVLHNSNTM
RLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAV
GSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAIL
AALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHQGVAVLGIALIAM
GEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSK
FSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMV
RLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILG
KSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQQTHTTPVLLAHGER
AELATEEFLPVTPILEGFVILRKN
Ligand information
>7uih Chain C (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SDISQSVSSAVQQYYSYYYPV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7uih Targeted degradation via direct 26S proteasome recruitment.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R680 Y681 R687 K712
Binding residue
(residue number reindexed from 1)		R368 Y369 R375 K400
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7uih, PDBe:7uih, PDBj:7uih
PDBsum7uih
PubMed36577875
UniProtQ13200|PSMD2_HUMAN 26S proteasome non-ATPase regulatory subunit 2 (Gene Name=PSMD2)

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