Structure of PDB 7uhl Chain A Binding Site BS01
Receptor Information
>7uhl Chain A (length=264) Species:
522373
(Stenotrophomonas maltophilia K279a) [
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APLPQLRAYTVDASWLQPMAPLQVADHTWQIGTEDLTALLVQTAEGAVLL
DGGMPQMAGHLLDNMKLRGVAPQDLRLILLSHAHADHAGPVAELKRRTGA
HVAANAETAVLLARGGSNDLHFGDGITYPPASADRIIMDGEVVTVGGIAF
TAHFMPGHTPGSTAWTWTDTRDGKPVRIAYADSLSAPGYQLKGNPRYPRL
IEDYKRSFATVRALPCDLLLTPHPGASNWNYAVGSKASAEALTCNAYADA
AEKKFDAQLARETA
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
7uhl Chain A Residue 301 [
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Receptor-Ligand Complex Structure
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PDB
7uhl
Time-resolved beta-lactam cleavage by L1 metallo-beta-lactamase.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
H105 H107 H181
Binding residue
(residue number reindexed from 1)
H82 H84 H158
Annotation score
1
Enzymatic activity
Enzyme Commision number
3.5.2.6
: beta-lactamase.
Gene Ontology
Molecular Function
GO:0008270
zinc ion binding
GO:0008800
beta-lactamase activity
Biological Process
GO:0017001
antibiotic catabolic process
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Molecular Function
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Biological Process
External links
PDB
RCSB:7uhl
,
PDBe:7uhl
,
PDBj:7uhl
PDBsum
7uhl
PubMed
36450742
UniProt
B2FTM1
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