Structure of PDB 7ubu Chain A Binding Site BS01

Receptor Information
>7ubu Chain A (length=708) Species: 4577 (Zea mays) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HEPEFIGSPVAADEARSNWPKRYGREELKARCHYRSAKVDNVVYCLGDDV
YVKAGENEADYIGRITEFFEGTDQCHYFTCRWFFRAEDTVINSLVSISVD
GHKHDPRRVFLSEEKNDNVLDCIISKVKIVHVDPNMDPKAKAQLIESCDL
YYDMSYSVAYSTFANISTRTATLLDLYSGCGGMSTGLCLGAALSGLKLET
RWAVDFNSFACQSLKYNHPQTEVRNEKADEFLALLKEWAVLCKKYVQQAD
EDSPLDKDEFVVEKLVGICYGGSDRENGIYFKVQWEGYGPEEDTWEPIDN
LSDCPQKIREFVQEGHKRKILPLPGDVDVICGGPPCQGISGFNRYRNRDE
PLKDEKNKQMVTFMDIVAYLKPKYVLMENVVDILKFADGYLGKYALSCLV
AMKYQARLGMMVAGCYGLPQFRMRVFLWGALSSMVLPKYPLPTYDVVVRG
GAPNAFSQCMVAYDETQKPSLKKALLLGDAISDLPKVQNHQPNDVMEYGG
SPKTEFQRYIRLSRKDMLDWSFGEGAGPDEGKLLDHQPLRLNNDDYERVQ
QIPVKKGANFRDLKGVRVGANNIVEWDPEIERVKLSSGKPLVPDYAMSFI
KGKSLKPFGRLWWDETVPTVVTRAEPHNQVIIHPTQARVLTIRENARLQG
FPDYYRLFGPIKEKYIQVGNAVAVPVARALGYCLGQAYLGESEGSDPLYQ
LPPSFTSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ubu Mechanistic basis for maintenance of CHG DNA methylation in plants.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		K195 A196 Y203 W224 F226 N258 N260 D263 C264 I265 D626 M641 A643 Y644 D645 E646 K649
Binding residue
(residue number reindexed from 1)		K53 A54 Y61 W82 F84 N116 N118 D121 C122 I123 D445 M460 A462 Y463 D464 E465 K468
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7ubu, PDBe:7ubu, PDBj:7ubu
PDBsum7ubu
PubMed35790763
UniProtQ9AXT8|CMT1_MAIZE DNA (cytosine-5)-methyltransferase 1 (Gene Name=MET2A)

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