Structure of PDB 7tz6 Chain A Binding Site BS01

Receptor Information
>7tz6 Chain A (length=446) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TATYAQALQSVPETQVSQLDNGLRVASEQSSQPTCTVGVWIDAGSRYESE
KNNGAGYFVEHLAFKGTKNRPGNALEKEVESMGAHLNAYSTREHTAYYIK
ALSKDLPKAVELLADIVQNCSLEDSQIEKERDVILQELQENDTSMRDVVF
NYLHATAFQGTPLAQSVEGPSENVRKLSRADLTEYLSRHYKAPRMVLAAA
GGLEHRQLLDLAQKHFSGLSGTYDEDAVPTLSPCRFTGSQICHREDGLPL
AHVAIAVEGPGWAHPDNVALQVANAIIGHYDCTYGGGAHLSSPLASIAAT
NKLCQSFQTFNICYADTGLLGAHFVCDHMSIDDMMFVLQGQWMRLCTSAT
ESEVLRGKNLLRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAEWESRIA
EVDARVVREVCSKYFYDQCPAVAGFGPIEQLPDYNRIRSGMFWLRF
Ligand information
Receptor-Ligand Complex Structure
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PDB7tz6 Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes.
Resolution2.88 Å
Binding residue
(original residue number in PDB)
Y284 G285
Binding residue
(residue number reindexed from 1)
Y284 G285
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:7tz6, PDBe:7tz6, PDBj:7tz6
PDBsum7tz6
PubMed37236355
UniProtP31800|QCR1_BOVIN Cytochrome b-c1 complex subunit 1, mitochondrial (Gene Name=UQCRC1)

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