Structure of PDB 7tuq Chain A Binding Site BS01
Receptor Information
>7tuq Chain A (length=124) Species:
9606
(Homo sapiens) [
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STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELP
Ligand information
>7tuq Chain C (length=3) Species:
2697049
(Severe acute respiratory syndrome coronavirus 2) [
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VKN
Receptor-Ligand Complex Structure
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PDB
7tuq
Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Resolution
2.68 Å
Binding residue
(original residue number in PDB)
L94 Y97 C136 N140
Binding residue
(residue number reindexed from 1)
L53 Y56 C95 N99
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7tuq
,
PDBe:7tuq
,
PDBj:7tuq
PDBsum
7tuq
PubMed
35716662
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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